Amino Acid Leucine: properties, excess and deficiency, leucine in Products #001

A large number of scientists simply attach great importance to the so-called essential amino acids. This is explained by the fact that such organic compounds, being unable to be produced independently in the human body, are extremely necessary for him to carry out a variety of biochemical reactions. The group of essential components of protein, along with other substances, also includes leucine.

Leucine from the point of view of the science of chemistry is an aliphatic amino acid. In animals and humans, this protein component is represented in the form of an L-isomer. However, this is not the only naturally occurring variety of an essential amino acid. There is also a D-optical isomer of leucine. In addition, both of these amino acid isomers can form mixtures called racemates.

In its pure form, leucine is a powdery substance that has no color. It is perfectly soluble in acids and alkalis and does not dissolve at all in diethyl ether. As for water, leucine has a rather limited ability to dissolve relative to it. The amino acid comes into contact with ethyl alcohol very badly. The melting point of substances depends entirely on the specific form of the protein component. If it is a racemate, then this indicator will be equal to 332C. Any of the amino acid isomers melts at a temperature of 293C without any impurities.

The chemical formula of leucine is as follows: HO2CCH(NH2)CH2CH(CH3)2. The name of the essential amino acid comes from the Greek word "leukos", which can be translated into Russian as "white". This name is due to the color scheme in which the organic substance is aged. For the first time the world learned about leucine in the first half of the XIX century: in 1820 it was isolated from wool and muscle fibers. And 84 years later, the scientist E. Fischer obtained the substance we are interested in artificially by synthesis as a result of a reaction between ammonia and 2-bromo-4-methylpentanic acid.

It has already been mentioned above that human and animal organisms are not capable of spontaneously forming the essential amino acid leucine. But plants and microflora can do it. In this case, leucine synthesis occurs from organic pyruvic acid. You and I, in order to get the optimal portion of this substance, need to consume foods saturated with it. If the above condition is met, leucine in different amounts is able to concentrate in the liver, kidneys, muscles, pancreas, spleen, blood serum and other tissues.

An essential amino acid is of tremendous importance for human health. It takes an active part in the processes of protein synthesis and breakdown. Thanks to leucine, a nitrogen balance is maintained in the internal environment of the body, without which sugar and protein metabolism reactions are impossible. Due to this organic compound, muscle cells and other tissues are always provided with the necessary amount of energy and are reliably protected from the decay process.

Under the influence of leucine, the immune system is in constant tone, regeneration properties increase, which means that the rate of wound healing also increases. With leucine, you will not recognize fatigue, and increasing the amount of glucose in the blood is simply impossible. It has a beneficial effect on bone tissue cells, stimulates the formation of somatropin ("growth hormone"), enhances insulin secretion, maintains an optimal level of water balance and albumin protein. As a result, leucine prevents the appearance of edema.

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